Sulfate is a synthetic version of a compound the
human body makes to stimulate the growth of
cartilage. The idea is that such compounds help
rebuild cartilage and reduce the symptoms of
The supplement is an acceptable treatment in
veterinary medicine, but the Arthritis Foundation
and the American College of Rheumatology have not
yet officially recommended it for humans, despite a
large body of evidence supporting its use and the
fact that it is considered a drug in several
countries around the world.
The United States Food
and Drug Administration does not approve any dietary
supplement, and, as such, at this time Glucosamine
is sold as a nutritional supplement and therefore
does not need evidence of safety and efficacy.
Glucosamine has been studied for over 20 years.
1-Cartilage formation & repair.
2-Athletes who experience connective tissue stress.
3-Joint pain relief.
Clucosamine & Chondroitin
Sulfate (CS) is a Glycosaminoglycans (GAG) found in
connective tissue and the nervous system, normally
attached to a protein core. CS GAG chains are
heteropolycaccharides of variable length comprised
of alternating sugars D-glucuronic acid (GlcA) and
N-acetyl-D-galactosamine (GalNac). In some of these
sugars, some GlcA residues are epimerized into
L-iduronic acid (IdoA), in which case the GAG chain
would be called dermatan Sulfate (DS).
In the matrix of cartilage, CS functions to maintain
osmotic pressure by absorbing water and therefore
help hydrate the cartilage. CS also contributes to
the flexibility and elasticity of the bone. Most
importantly, it serves as a chondroprotective agent
by protecting the cartilage against enzymatic
reactions and free radical damage (including nitric
oxide released by chondrocytes).
1-Treatment of Arthritis.
(MSM) is a naturally-occurring sulfur compound.
Many years of clinical use at Oregon Health Sciences
University has demonstrated that MSM provides pain
relief and anti-inflammatory benefits.
Some of MSM's essential functions in the body
include maintaining the structure of the proteins in
the body, helping the formation of keratin which is
essential for hair and nail growth. Some studies
demonstrated the effectiveness of a natural
substance Lignisul MSM on acute athletic injuries,
such as muscle sprains and strains.
1-Inhibition of pain impulses along nerve fibers
2-Lessening of inflammation.
3-Increase in blood supply.
4-Reduction of muscle spasm.
5-Softening of scar tissue.
6-Hair and nail growth.